The information in this post is based on Ultimaker Cura 4.7.1. It may or may not be valid for other versions.
As of Cura 4.7.1, the popular Artillery Sidewinder X1 printer is still not supported out of the box. This is my first (and so far only) 3D printer and I’m quite happy with it, but it’s always a bit annoying to have to find and install custom profiles when Cura is updated, so I’ve been stuck on a much older version for a long time.
However, I recently discovered that the Sidewinder X1 works perfectly well with Cura’s “Custom FFF printer” profile as long as you make a few adjustments, like so:
When you add a printer, choose “Add a non-networked printer” and then under “Custom” choose “Custom FFF printer”.

Then click “Add”, which takes you to the Machine Settings dialog.
Here you need to change the size (X = 300, Y = 300 and Z = 400) of the printer, tick the checkbox for Heated bed and make sure to set the G-code flavor to “RepRap”. The rest should be good at defaults, but check to make sure it’s set like in this screenshot

Then change to the “Extruder 1” tab page, where you need to make sure that “Compatible material diameter” is set to 1.75 mm (it defaults to 2.85 mm). If you use a non-standard nozzle size you will also need to change that here, but in my case the printer had a 0.4 mm nozzle at this time, so I didn’t change it:

Click “Next” and you’re done 🙂